Understanding Lupus Mouth Sores or Ulcers (2024)

Mouth sores can be a symptom of lupus or a warning sign of a lupus flare. They require medical treatment but may or may not be painful.

Lupus is a chronic autoimmune condition that causes inflammation throughout the body. Symptoms of lupus include widespread pain, rashes, and fatigue. For many people, lupus comes and goes in episodes called flares.

Mouth sores are a common lupus symptom and are often the first sign of a lupus flare. When these painful red bumps appear, it’s a good time to contact your doctor.

People with lupus can develop mouth sores during flares and during lupus remission. During lupus remission, mouth sores are typically a side effect of a medication that’s been prescribed to treat lupus.

During lupus flares, mouth sores are part of the system-wide immune inflammation that causes a range of other lupus symptoms such as rashes and joint pain. Mouth sores during a flare are more common at certain times.

This includes during:

  • severe flares
  • pregnancy
  • periods of hormonal changes
  • periods of low vitamin B12
  • periods of iron-deficiency anemia
  • extreme stress
  • a severe infection

Lupus mouth sores vs. canker sores

Canker sore is a broad term that’s used to talk about all mouth sores that aren’t caused by recent injuries or viral infections. Mouth ulcers and mouth sores are types of canker sores. However, canker sores can be treated at home and aren’t a cause for concern — unless you’re immunosuppressed.

If you have lupus and notice any sores inside your mouth at any time, it’s always important to let your doctor know. Mouth sores can be a sign your lupus is flaring and that treatment is needed.

Was this helpful?

About 40% of people with lupus get mouth sores when they’re not experiencing flares. This is normally linked to medications. These ulcers are almost always painless.

Mouth ulcers are also very common during flares for people with lupus. Some people experience pain with this ulcer type while others don’t.

The appearance of lupus mouth sores depends on the type. There are two types of lupus mouth sores:

  1. The first type happens outside of flares as a side effect of many lupus medications. These sores are raised white bumps that are surrounded by red lines and are usually painless.
  2. The second type happens during a flare as a symptom of inflammation. These sores are red with a white halo or white lines extending around them and can be painful. They often appear on the roof of the mouth but can develop anywhere.

Picture of lupus-related mouth sores or ulcers

This image will give you an example of lupus mouth sores.

Share on Pinterest

It’s important to talk with your doctor if you notice mouth sores. Seeing a dentist regularly is a good idea for people with lupus, especially because mouth sores can be painless and located on the roof of your mouth. You may not know that they’ve developed.

However, since they can signal a lupus flare, it’s best to keep an eye out for them. If you or a dentist spots a mouth ulcer, let your doctor know. They order more testing and decide on the best treatment.

Typically, treating your lupus flare will also treat your mouth sores. You might also have treatment to help relieve any pain caused by mouth sores. Common treatments include:

  • adjusting or changing medications
  • topical corticosteroids
  • oral corticosteroids
  • antimalarials
  • medicated mouthwashes and toothpaste
  • pain-relieving and anti-inflammatory oral tooth gels and mouthwashes

Preventing pain from lupus mouth sores

Mouth sores can be painful. Your doctor can prescribe or recommend treatments that might help, such as mouth sprays, medicated mouthwashes, and pain relieving gels.

You can add to those recommendations with products from your local grocery or drug stores, such as soft-bristled toothbrushes, and nonabrasive fluoride toothpaste.

Your diet can also have an effect on mouth sore pain. To help manage mouth sores, it’s a good idea to:

  • avoid spicy food while sores are active
  • avoid acidic foods while sores are active
  • avoid popcorn, crackers, and other hard foods while sores are active
  • eliminate gum from your diet
  • limit your coffee consumption
  • limit foods that could increase the risk of mouth sores, such as peanuts, almonds, strawberries, tomatoes, cheese, wheat flour, and chocolate

How long do lupus mouth sores or ulcers last?

Lupus mouth sores typically clear up after several days of treatment. In some cases, such as if your lupus flare is severe, it might take a week or two.

If sores last for longer than 3 weeks, it’s a good idea to contact your doctor again. This could be a sign that treatment isn’t effective or of infection.

Was this helpful?

Mouth sores are a common symptom of lupus. They can develop during flares and during lupus remission. When they happen outside of lupus flares, they’re typically a side effect of lupus medication.

These sores aren’t painful and are easily treated. When sores happen as part of a lupus flare, they can result in pain and are a sign of wider inflammation.

Sores are resolved as part of treatment for the lupus flare. This commonly includes medications such as corticosteroids. You can also manage the pain of mouth ulcers with treatments such as medicated mouthwashes.

Understanding Lupus Mouth Sores or Ulcers (2024)

FAQs

Understanding Lupus Mouth Sores or Ulcers? ›

Ulcers that occur with lupus are red with a white halo. They most often appear on the roof of the mouth, inside the cheeks, or on the lips. And they may or may not be painful. Examine your mouth regularly to make sure you're aware of any mouth sores you may have.

What does a lupus mouth ulcer look like? ›

They have a non-characteristic coloring of red or white – or both red and white – and are painless. Oral lesions associated with active disease are usually red ulcers surrounded by a white halo and white radiating lines.

What mouth problems does lupus cause? ›

Inflammation from lupus can cause gum disease, also called periodontitis. If you have gum disease, you may experience: Red, swollen, or tender gums. Bleeding in the gums, especially when you brush or floss.

What autoimmune disease causes ulcers in the mouth? ›

Almost everyone with Behçet's disease develops mouth ulcers. The ulcers may look the same as normal mouth ulcers, but can be more numerous and painful. They most often develop on the tongue, lips, gums and the insides of the cheeks.

What are the oral lesions of systemic lupus? ›

Systemic lupus erythematosus (SLE) is an autoimmune disease with various oral manifestations, including ulceration, white keratotic plaques, oral discoid lupus erythematosus, oral lichen planus (OLP)-like lesions, non-specific erythema, purpura, petechiae, and cheilitis, which resemble lesions of other systemic ...

What is the biggest indicator of lupus? ›

Anti-Smith Antibody Tests

The anti-Smith antibody, also known as the anti-Sm antibody, targets the body's own proteins and is found almost exclusively in people with lupus. Though not all people with lupus have this antibody, those who do usually receive a diagnosis of lupus.

What do lupus blisters look like? ›

Discoid lupus lesions: These thick and disk-shaped lesions often appear on the scalp or face and can cause permanent scarring. They may be red and scaly but do not cause pain or itching. Subacute cutaneous lesions: These may look like patches of scaly skin or ring-shaped sores.

How to get rid of lupus mouth sores? ›

Visiting the doctor

Often, the medicines prescribed by doctors to control SLE are enough to treat or at least decrease the lupus mouth sores to an extent. Some doctors prescribe steroid tablets or oral gels, while others resort to anti-malarial drugs.

What does your tongue look like if you have lupus? ›

People with lupus can develop red ulcers on the lips, the tongue, and the inside of the mouth. A white halo surrounds these ulcers, and they may or may not cause irritation. Those experiencing a “flare-up” can develop ulcers quite quickly.

What is Sjögren's tongue? ›

The main symptoms of Sjögren's disease are: Dry mouth. Your tongue and your throat will feel dry and chewing and swallowing may be difficult or painful. Dry eyes. Your eyes may burn or itch or feel as if you have a piece of sand in your eye.

Why am I getting continuous mouth ulcers? ›

The most common cause is injury (such as accidentally biting the inside of your cheek). Other causes include aphthous ulceration, certain medications, skin rashes in the mouth, viral, bacterial and fungal infections, chemicals and some medical conditions. An ulcer that won't heal may be a sign of mouth cancer.

What vitamin deficiency is linked to mouth ulcers? ›

For instance, canker sores, a type of mouth ulcer, are often the result of deficiencies in iron or B vitamins. In a small older study, around 28% of patients with recurring mouth ulcers had deficiencies in thiamine (vitamin B1), riboflavin (vitamin B2), pyridoxine (vitamin B6) or a combination of the vitamins.

What does lupus do to your lips? ›

The different types of lupus can also cause the following changes to your skin: Dry, chapped lips. Blister-like rash. Lacy pattern on the skin called livedo reticularis.

Where are lupus mouth sores located? ›

The Centers for Disease Control and Prevention (CDC) explain that mouth ulcers in lupus usually appear on the roof of the mouth. However, the sores may also occur on the gums, inside the cheeks, or on the lips.

How does lupus affect the mouth? ›

Oral Complications

Lupus can affect your salivary glands and cause dry mouth. Dry mouth can increase the risk of developing cavities and other infections. If you have lupus, be sure to tell your dentist. Together, you can keep your mouth healthy.

What percentage of SLE patients have oral lesions? ›

Out of 176 patients with active SLE, 78.4% (n = 138) were found to have at least one mucosal lesion in the oral cavity. In patients with inactive SLE, oral mucosal lesions were present in only 8% (n = 26). Around 51.1% of patients with active SLE presented with an aphthous ulcer in the oral mucosa.

Are SLE oral ulcers painful? ›

Lesions are usually painless, although discoid lesions may be painful. Aphthous ulcers are most common along the hard palate, but may also occur along the buccal mucosa or along the vermillion border. Treatment for SLE typically involves hydroxychloroquine and/or prednisone, depending on other disease manifestations.

What does an infected ulcer look like in mouth? ›

Mouth ulcers look like a shallow sore with a white/grey top and a red rim. They can occur as a single ulcer or in a cluster.

What does a traumatic mouth ulcer look like? ›

Traumatic ulcers mostly appear as erythematous, raised edges with a yellowish-white necrotic pseudomembrane which can be easily removed. The ulcerations involving the vermillion border of the lip typically have crusted appearance. Traumatic ulcers mostly heal within ten days after the removal of injurious factors.

References

Top Articles
Latest Posts
Article information

Author: Dean Jakubowski Ret

Last Updated:

Views: 6338

Rating: 5 / 5 (50 voted)

Reviews: 81% of readers found this page helpful

Author information

Name: Dean Jakubowski Ret

Birthday: 1996-05-10

Address: Apt. 425 4346 Santiago Islands, Shariside, AK 38830-1874

Phone: +96313309894162

Job: Legacy Sales Designer

Hobby: Baseball, Wood carving, Candle making, Jigsaw puzzles, Lacemaking, Parkour, Drawing

Introduction: My name is Dean Jakubowski Ret, I am a enthusiastic, friendly, homely, handsome, zealous, brainy, elegant person who loves writing and wants to share my knowledge and understanding with you.